Figure 3.

Actin regulatory protein-binding interfaces and posttranslational modification sites overlap with filament-specific cation sites. (A) Residues participating in the actin-cofilin interface (yellow) (78); (inset) 90° turn and zoom to cation sites where site residues in the cofilin binding interface are highlighted (orange). (B) Acetylation, ADP-ribosylation, arginylation, carbonylation, malonylation, methylation, nitrosylation, oxidation, phosphorylation, and ubiquitylation sites (83) are shown (blue) for longitudinal subunits; (inset) 90° turn and zoom to cation sites where modifiable site residues are highlighted (purple). To see this figure in color, go online.