Table 4.
Changes in saliva flow rate, salivary secretory immunoglobulin A concentration, and salivary secretory immunoglobulin A secretion rate during the study period
| 0 week | 4 weeks | 8 weeks | 12 weeks | |
|---|---|---|---|---|
| Saliva flow rate (ml/5 min)† | ||||
| Placebo | 1.1 ± 0.8 | 1.2 ± 0.8 | 1.2 ± 0.8 | 1.2 ± 0.7 |
| b240 | 1.5 ± 0.9 | 1.5 ± 0.9 | 1.7 ± 0.9 | 1.7 ± 0.9 |
| SIgA concentration (µg/ml) | ||||
| Placebo | 29.3 ± 11.2 | 29.7 ± 16.8 | 31.8 ± 17.1 | 28.0 ± 16.6 |
| b240 | 26.6 ± 11.4 | 30.3 ± 16.6 | 29.4 ± 23.1 | 27.6 ± 19.0 |
| SIgA secretion rate (µg/5 min)† | ||||
| Placebo | 27.1 ± 19.0 | 32.2 ± 29.4 | 39.2 ± 41.2 | 30.8 ± 22.3 |
| b240 | 35.1 ± 21.3 | 42.2 ± 31.0 | 47.0 ± 42.4 | 44.5 ± 32.0 |
Values are presented as means ± SD. †Treatment × time interaction, p<0.05.