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. 2013 Oct 15;45(23):1168–1185. doi: 10.1152/physiolgenomics.00022.2013

Fig. 4.

Fig. 4.

Examples of delayed downregulation of metabolic and structural/contractile genes in MuRF1 KO mice after DEN. Results for 3 and 14 days post-DEN for metabolic enzymes are shown in A, only results for 3 days post-DEN for structural/contractile genes are shown in B. White bars, controls; black bars, DEN or DEX treated. #Significantly different from between groups, P < 0.05; *Different from controls in same group, P < 0.05. PHKG1, glycogen phosphorylase gamma1 subunit; GPD1, glycerol 3-phosphate dehydrogenase 1 (soluble); ENO3, muscle-specific enolase; LDHA, lactate dehydrogenase A; MYH1, myosin heavy chain IIx; MYH2, myosin heavy chain IIa; MYH4, myosin heavy chain IIb; MYLK2, myosin light chain kinase 2; MYBPC2, myosin binding protein C2 (skeletal muscle); ACTN2, α-actinin2.