Fig. 6.

MuRF1 KO mice show blunted upregulation of HDAC4 and myogenin protein expression after denervation. A: microarray results for HDAC4 (top) and myogenin (MYOG, bottom) after 3 and 14 days DEN. B: Western blot of HDAC4, MYOG, and glyceraldehyde 3-phosphate dehydrogenase, showing results from controls (Con) vs. 3 day DEN WT and KO triceps surae. C: quantification of Western blot shown in B. White bars, controls (−DEN); black bars, +DEN. #Significantly different from between groups, P < 0.05, *different from controls in same group; P < 0.05.