Table 1.
Obesity increases left ventricular mass with preservation of volumes and ejection fractions in mice
| Low-fat diet | High-fat diet | Change due to high-fat diet | p value | |
|---|---|---|---|---|
| Left ventricular mass (mg) |
100 ± 8 |
115 ± 8 |
+15% |
0.032 |
| Left ventricular end-diastolic volume (μL) |
61 ± 8 |
58 ± 5 |
−6% |
0.548 |
| Left ventricular end-systolic volume (μL) |
25 ± 5 |
21 ± 3 |
−16% |
0.222 |
| Left ventricular mass to end-diastolic volume ratio (mg/μL) |
1.6 ± 0.3 |
2 ± 0.2 |
+22% |
0.032 |
| Left ventricular ejection fraction (%) | 59 ± 3 | 64 ± 3 | +7% | 0.056 |
Values are mean ± standard deviation, n = 5 in each group.