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. 2013 Mar 1;3(1):26–35. doi: 10.11599/germs.2013.1034

Figure 1. Diagrammatic representation for the production of DNA vaccine.

Figure 1.

A) A gene gun is an instrument containing gold particles having DNA coated on it for DNA vaccines. B) The gold particle fired from the gene gun into the target cell gets integrated into the DNA of the target cell. C) Transcription takes place leading to the formation of mRNA. D) mRNA is transported from the nucleus for translation to the form of protein antigen. E) The expressed antigen enters into the antigen-processing pathway. F) The foreign antigenic peptides presented on host cell MHC evoke cell mediated and humoral responses.

DNA deoxyribonucleic acid; MHC major histocompatibility complex; mRNA messenger ribonucleic acid.