Table 1.
Characteristics | Normal (n = 92) | Esophagitis (N = 50) | Mild dysplasia (N = 37) | Moderate dysplasia (N = 37) | Severe dysplasia (N = 15) |
---|---|---|---|---|---|
Males, N (%) |
43 (47) |
12 (24) |
17 (46) |
16 (43) |
7 (47) |
Age, median years (Q1-Q3) |
54 (51–57) |
53 (51–57) |
54 (51–58) |
55 (53–57) |
55 (52–57) |
BMI, median (Q1-Q3) |
23.5 (21.5-24.8) |
23.2 (21.8-25.4) |
23.1 (20.8-25.2) |
22.7 (20.4-24.8) |
24.5 (22.5-27.2) |
Ever smoke cigarettes, N (%) |
28 (30) |
11 (22) |
10 (27) |
11 (30) |
5 (33) |
Drink alcohol, any, N (%) |
11 (12) |
2 (4) |
2 (5) |
2 (5) |
1 (7) |
Hypertension, yes, N (%) |
64 (68) |
34 (68) |
30 (81) |
27 (73) |
11 (73) |
Telomere lengtha, mean (SD) |
0.92 (0.17) |
0.90 (0.16) |
0.96 (0.18) |
0.95 (0.17) |
0.97 (0.24) |
Telomere lengtha, median (Q1-Q3)a | 0.92 (0.78-1.05) | 0.88 (0.80-1.00) | 0.93 (0.84-1.06) | 0.94 (0.82-1.09) | 0.93 (0.85-0.98) |
aCalculated as telomeric DNA (T) divided by amount of single-copy control gene DNA (S) to produce the relative measurement of telomere length (T/S ratio).
Abbreviations: SD, standard deviation; Q1, first quartile; Q3, third quartile; BMI, body mass index.