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. Author manuscript; available in PMC: 2014 Jan 7.
Published in final edited form as: J Alzheimers Dis. 2012;31(1):10.3233/JAD-2012-120328. doi: 10.3233/JAD-2012-120328

Fig. 2.

Fig. 2

Dexamethasone elevates RIPA-soluble Aβ40 peptides. A) Dexamethasone treatment (n = 6, closed bars) elevates RIPA soluble Aβ40 without altering RIPA soluble Aβ42, FA soluble Aβ40 or FA insoluble Aβ42 in the brains of Tg2576 mice compared to controls (n = 5, open bars) (*p < 0.004). B) Representative western blots for AβPP, ADAM-10, BACE-1, PS1, PEN-2, APH-1, and NCT in brain homogenates from Tg2576 mice treated with either PBS (control) (n = 5 open bars) or 5 mg/kg dexamethasone (Dex) (n = 6, closed bars). C) Densitometric analyses of the immunoreactivities to the antibodies shown in panel B (control: open bars; dexamethasone: closed bars).