The fine structure of human ovarian tissue. Primordial follicles (A) and stroma (B) of vitrified-warmed group. Pr, primordial follicle; nu, nucleolus; nm, nuclear membrane; n, nucleus; o, ooplasm; m, mitochondria; gc, granulosa cell; sc, stromal cell. The ultrastructure of nucleus of oocyte and granulosa cells of primary follicle was well preserved and was similar to the non-vitrified group. The oocyte had a euchromatic nucleus at the germinal vesicle stage. No nucleus fragmentation, shrinkage of cell membrane and vacuoles within cytoplasm of oocyte and granulosa were seen