Table 3.
Genotype distribution of CD226 rs727088 polymorphism in rheumatoid arthritis (RA) patients and normal subjects
| rs727088 G>A |
RA n
(%) |
Control n
(%) |
a
OR
(95%CI) |
P value |
|---|---|---|---|---|
| Codominant | ||||
| GG | 29 (29.0) | 23 (22.1) | 1.00 | - |
| GA | 53 (53.0) | 52 (50.0) | 1.0 (0.50-1.99) | 0.997 |
| AA | 18 (18.0) | 29 (27.9) | 0.73 (0.31-1.72) | 0.467 |
| Dominant | ||||
| GG | 29 (29.0) | 23 (22.1) | 1.00 | - |
| GA+AA | 71 (71.0) | 81 (77.9) | 1.09 (0.56-2.11) | 0.802 |
| Recessive | ||||
| GG+GA | 82 (82.0) | 75 (72.1) | reference | - |
| AA | 18 (18.0) | 29 (27.9) | 0.74 (0.36-1.49) | 0.391 |
| Alleles | ||||
| G | 111 (55.5) | 98 (47.1) | 1.00 | - |
| A | 89 (44.5) | 110 (52.9) | 0.71 (0.48-1.05) | 0.093 |
aadjusted for sex and age; OR, odds ratio; CI, confidence intervals