ICE (A), PRO (B), and CDD (C) scores from baseline to week 48 in patients receiving natalizumab
*Average over three visits within the 45 days prior to the first natalizumab infusion. Positive (upward) slope indicates improvement. CDD, Code Substitution Delayed Memory; ICE, Index of Cognitive Efficiency; NS, not significant; PRO, Procedural Reaction Time; SEM, standard error of the mean.