Advantages and Disadvantages of Using Cord Blood for Hematopoietic Cell Transplantation Compared with Bone Marrow
Advantages | Disadvantages |
---|---|
Ease and safety of obtaining cells without harm to baby or mother |
Slower time to neutrophil, platelet, and immune cell recovery |
Efficient storage as units of HLA-typed cells in cryopreserved form in CB banks |
Higher rate of graft failure |
Available for immediate use after storage |
Limited number of CB cells collected from babies at birth |
Elicitation of a lower level of GVHD than BM cells |