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. 2013 Dec 1;22(Suppl 1):103–110. doi: 10.1089/scd.2013.0382

Advantages and Disadvantages of Using Cord Blood for Hematopoietic Cell Transplantation Compared with Bone Marrow

Advantages Disadvantages
Ease and safety of obtaining cells without harm to baby or mother
Slower time to neutrophil, platelet, and immune cell recovery
Efficient storage as units of HLA-typed cells in cryopreserved form in CB banks
Higher rate of graft failure
Available for immediate use after storage
Limited number of CB cells collected from babies at birth
Elicitation of a lower level of GVHD than BM cells