Table 3.
Comparison of Insulin-like growth factor-1 (ng/mL) levels in the study groups
| Time | APN and ROP (n = 2) | APN and no ROP (n = 38) | P. value* | CPN and ROP (n = 11) | CPN and no ROP (n = 24) | P. value* |
|---|---|---|---|---|---|---|
| First day | 18.2 (1.1) | 19.1 (1.4) | 0.4 | 17.6 (1.6) | 18.0 (1.8) | 0.5 |
| 1st week | 20.3 (1.2) | 21.5 (1.1) | 0.1 | 14.5 (2.1) | 15.6 (1.5) | 0.08 |
| 2ndweek | 24.1 (1.7) | 25.4 (1.3) | 0.2 | 20.2 (1.5) | 21.1 (1.8) | 0.2 |
| 3rd week** | 29.1 (1.9) | 31.8 (1.5) | 0.01 | 24.1 (1.6) | 25.2 (1.8) | 0.08 |
| 4th week | 34.7 (3.2) | 37.5 (1.8) | 0.04 | 26.3 (1.8) | 27.2 (1.6) | 0.1 |
| 6th week | 37.9 (3.7) | 39.8 (1.1) | 0.04 | 31.2 (2.9) | 32.8 (2.1) | 0.07 |
APN: Aggressive parenteral nutrition; CPN: Conventional parenteral nutrition
*
ANOVA t-test
**
3rd week correlation coefficient was revelaled [IGF-1 (r2:-0.65), IGFBP3 (r2:-0.51)]