Table 1.
Description of the HITEA project participants, not included and included in the study
| |
|
|
LISA |
PIAMA |
INMA |
|||
|---|---|---|---|---|---|---|---|---|
| |
|
|
Not included |
Included |
Not included |
Included |
Not included |
Included |
| n = 213 | n = 182 | n = 309 | n = 244 | n = 126 | n = 355 | |||
|
Population characteristics |
|
|
|
|
|
|
||
| |
Sex (female): n(%) |
104 (48.8) |
76 (41.8) |
139 (45) |
127 (52.1) |
57 (45.2) |
177 (49.9) |
|
| |
Age at FeNO measurement (years): mean (sd) |
- |
10.2 (0.2) |
- |
8.0 (0.3) |
- |
11.5 (0.7) |
|
| |
FeNO (ppb): GM (Gsd) |
- |
14.7 (2.0) |
- |
10.2 (2.0) |
- |
12.4 (2.3) |
|
| |
Asthma (4 to 10 years old*): n (%) |
9 (8.9) |
10 (6.1) |
20 (14.5) |
19 (10.6) |
33 (10.3) |
41 (10.8) |
|
| |
Atopy (sIgE ≥0.35U/mL)
a
: n (%) |
8 (53.3) |
80 (47.6) |
45 (43.3) |
71 (36.8) |
7 (14.3) |
36 (16.1) |
|
| |
Reported allergies (4 to 10 years old*): n (%)
bd
|
50 (39.4) |
46 (27.1) |
64 (41.6) |
86 (39.8) |
41 (51.3) |
117 (33.9) |
|
| |
Parental education: n (%)
d
|
|
|
|
|
|
|
|
| |
|
Secondary school |
38 (18.4) |
20 (11.4) |
98 (37.3) |
80 (33.3) |
38 (31.7) |
130 (38.4) |
| |
|
Higher than secondary school |
159 (76.8) |
148 (84.6) |
131 (49.8) |
140 (58.3) |
12 (10.0) |
67 (19.8) |
| |
Parental asthma: n (%) |
25 (12.3) |
21 (11.9) |
93 (30.8) |
84 (35.0) |
17 (14.1) |
34 (9.6) |
|
| |
Parental smoking at the age of 10 years*: n (%) |
9 (8.7) |
11 (6.4) |
9 (6.1) |
10 (5.0) |
28 (45.2) |
115 (35.8) |
|
|
Indoor exposures |
|
|
|
|
|
|
||
| |
Endotoxin concentrations (EU/mg): GM (Gsd) |
22.6 (2.5) |
23.5 (2.4) |
23.2 (3.7) |
20.6 (3.2) |
4.0 (6.3) |
3.1 (6.4) |
|
| |
EPS concentrations (U/mg): GM (Gsd) |
46.6 (2.5) |
48.4 (2.1) |
29.1 (2.8) |
32.9 (3.5) |
119.9 (2.7) |
116.4 (2.5) |
|
| |
Glucan concentrations (ug/mg): GM (Gsd) |
1.9 (1.7) |
2.0 (1.7) |
1.6 (2.1) |
1.8 (2.4) |
- |
- |
|
| |
Dampness at home (first 2 years of life)
c
|
74 (35.1) |
62 (34.3) |
159 (64.9) |
121 (54.8) |
72 (57.6) |
221 (63.3) |
|
| |
Cat ownership: n (%)
c
|
|
|
|
|
|
|
|
| |
|
Ever during the first 2 years of life |
25 (20.2) |
23 (13.8) |
79 (42) |
59 (27.2) |
15 (20.3) |
68 (19.3) |
| |
|
Ever after the first 2 years of life |
17 (13.7) |
26 (15.6) |
12 (6.4) |
19 (8.8) |
10 (13.5) |
30 (8.5) |
| |
Dog ownership: n (%)
bcd
|
|
|
|
|
|
|
|
| |
|
Ever during the first 2 years of life |
16 (13.5) |
8 (5.0) |
51 (28.5) |
31 (14.5) |
45 (47.9) |
143 (40.9) |
| Ever after the first 2 years of life | 16 (13.5) | 16 (10.1) | 32 (17.9) | 16 (7.5) | 19 (20.2) | 45 (12.9) | ||
sd: standard deviation; GM: geometric mean; Gsd: geometric standard deviation; FeNO: fractional exhaled nitric oxide; Reported allergies: eczema, rhinitis or hay fever.
*8 years in PIAMA; aLISA n not included = 15 and n included = 168, PIAMA n not included = 104 and n included = 193, INMA n not included = 49 and n included = 224; bp-value < 0.05 of the difference between included and not included in LISA; cp-value < 0.05 of the difference between included and not included in PIAMA; dp-value < 0.05 of the difference between included and not included in INMA.