Table 2.

Correlation between number of FoxP3+ cells in SLN and pathological characteristics

Parameter	FoxP3 Cell Number	p value
Tumor type
Ductal	308.8 ± 151.9	Ductal vs. lobular = NS
Lobular	274.8 ± 86.1	Ductal vs. mixed = NS
Mixed	274.2 ± 86.6	Lobular vs. mixed = NS
Tumor grade
Well differentiated	314.2 ± 115.8	Well vs. moderate = NS
Moderately differentiated	301.5 ± 140.2	Well vs. poor = NS
Poorly differentiated	299.3 ± 161.3	Moderate vs. poor = NS * Well vs. moderate + poor = NS
HER2/neu status
Not overexpressed	298.2 ± 142.7	NS
Overexpressed	305.5 ± 144.0
Lymphovascular invasion
No	302.6 ± 167.6
Yes	304.4 ± 133.4	NS
SLN status
Negative	278.2 ± 107.2	Neg vs. ITC = NS; ITC vs. micro = NS
Isolated tumor cells	335.5 ± 178.2	Neg vs. micro = NS; ITC vs. Macro = NS
Micrometastases	296.1 ± 160.5	Negative vs. macro = NS
Macrometastasis	314.0 ± 141.1	Micro vs. macro = NS Negative vs. ITC + Micro + Macro = NS

^*Due to their similarity to each other and their relative dissimilarity with the well-differentiated tumors in terms of mean FoxP3+ cell number, the moderate and poor tumor grades were combined. Because of the low number of well-differentiated tumors, lack of significant difference may reflect low statistical power.