Table 1.
The average slope and water content of MCS-acetate, MCS-lactate, MCS-malate, MCS-succinate, and MCS-citrate, and their corresponding acid dissociation constant (pKa)
| Formulation | Slope | Water content | Acid | pKa |
|---|---|---|---|---|
| MCS-citrate | 19.56 | 7.52 | Citric acid | pKa1=3.15 pKa2=4.77 pKa3=6.40 |
| MCS-malate | 14.00 | 13.24 | Malic acid | pKa=3.4 pKa2=5.13 |
| MCS-lactate | 13.69 | ND | Lactic acid | pKa=3.86 |
| MCS-succinate | 13.79 | ND | Succinic acid | pKa1=4.2 pKa2=5.6 |
| MCS-acetate | 13.64 | 21.26% | Acetic acid | pKa=4.76 |
Abbreviations: MCS, chitosan 190–310 kDa; ND, data not done.