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. 2013 Dec 27;9:231–242. doi: 10.2147/IJN.S55541

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© 2014 Xu et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Fluorescent microscope images of A549 cells incubated with coumarin-6-loaded Tet-NPs.

Notes: (A) Cells incubated with coumarin-6 loaded Tet-NPs at 37°C. (B) Cells incubated with coumarin-6 loaded Tet-NPs at 4°C. (C) Cells incubated with both coumarin-6 loaded Tet-NPs and NaN₃ at 37°C. Magnification =400X. (D) The cellular uptake efficiency of coumarin-6 loaded Tet-NPs detected by HPLC. **Represents P<0.01 versus control.

Abbreviations: Tet-NPs, tetrandrine-loaded poly(N-vinylpyrrolidone)-block-poly(ε-caprolactone) nanoparticles; NaN₃, sodium azide; HPLC, high-performance liquid chromatography.