Table 2.
Genotype frequency of A69S (ARMS2), I62V (CFH), and Y402h (CFH) polymorphisms in Japanese controls and Japanese patients with retinal angiomatous proliferation
| Genotype | rs10490924 (A69S)
|
rs800292 (I62V)
|
rs1061170 (Y402H)
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| TT | TG | GG | GG | GA | AA | CC | CT | TT | |
| Controls (n=1,351)26 | 196 (14.6%) | 638 (47.8%) | 502 (37.6%) | 456 (34.1%) | 649 (48.5%) | 233 (17.4%) | 8 (0.6%) | 160 (11.9%) | 1,174 (87.5%) |
| Patients (n=36)26 | 31 (86.1%) | 3 (8.3%) | 2 (5.6%) | 20 (55.6%) | 11 (30.6%) | 5 (13.8%) | 0 (0%) | 5 (14.3%) | 30 (85.7%) |
| Patients (n=51)27 | 39 (76.5%) | 10 (19.6%) | 2 (3.9%) | 29 (56.9%) | 20 (39.2%) | 2 (3.9%) | ND | ND | ND |
| Patients (n=8) (in present study) | 7 (87.5%) | 1 (12.5%) | 0 (0%) | 0 (0%) | 0 (0%) | 8 (100%) | 0 (0%) | 2 (25%) | 6 (75%) |
Note: Risk alleles are shown in bold.
Abbreviation: ND, not described.