Table 1.
Patient* | Age (yrs)† | Histology | Stage‡/grade | Chemotherapy Treatment | Specimen Type | Patient Status§ |
---|---|---|---|---|---|---|
A | 60 | Serous/high grade OVCA | IIIC/3 | Post surgery: 8 cycles taxane/carboplatin and etoposide | Ascites at surgery, frozen | DOD, 19 months |
B | 65 | Serous/papillary OVCA | NIC/3 | Pre specimen collection: 3 cycles taxane/cisplatin, recurrence. Post specimen: 4 cycles taxane/cisplatin | Ascites from paracentesis, frozen | DOD, 11 months |
C | 65 | Serous/high grade OVCA | IIIC/3 | Neoadjuvant pre specimen: 3 cycles taxane/carboplatin. Post surgery: 6 cycles paclitaxel/carboplatin IP | Ascites at surgery, frozen | DOD, 10 months |
D | 51 | Serous/papillary OVCA | IIIC/3 | Post surgery: 6 cycles taxane/cisplatin | Ascites at surgery, frozen | DOD, 13 months |
E | 54 | Serous/high grade OVCA | IIIC/3 | Post surgery: 6 cycles taxane IV, cisplatin IP | Ascites at surgery, frozen | AWD, 11 months |
F | 74 | Serous/papillary OVCA | IIIC/3 | Post surgery: 6 cycles taxane/cisplatin | Ascites at surgery, frozen | AWD, 11 months |
G | 69 | Clear cell OVCA | IIIC/3 | None | Ascites at surgery, fresh | DOD, 2 months |
H | 86 | Carcinosarcoma [Malignant Mixed Mesodermal] | IIB/3 | None | Ascites at surgery, fresh | AWD, 6 months |
I | 46 | Serous/high grade OVCA | IIIC/3 | Post surgery: 8 cycles taxane/carboplatin | Metastasis to omentum, fresh | NED, 10 months |
All patients were chemo naive at the time of surgery, except Patients B and C, who received standard taxane/platinum combination chemotherapy.
At the time of diagnosis.
International Federation of Obstetrics and Gynecology (FIGO) System.
Post-Diagnosis; DOD = died of disease; AWD = alive with disease; NED = alive with no evidence of disease.