Table 2. The relationship between clinicopathological factors and baseline inflammatory scores (NLR, PLR) in patients with advanced solid tumours considered for experimental treatments (Training Set).
Variable | NLR<5 | NLR≥5 | P | PLR<300 | PLR≥300 | P |
Gender, M/F | 24/46 | 14/29 | 0.85 | 28/46 | 10/29 | 0.19 |
Age, <65/≥65 | 34/36 | 29/14 | 0.05 * | 37/37 | 26/13 | 0.09 |
ECOG PS, 0–1/≥2 | 61/8 | 24/17 | <0.001 * | 56/17 | 29/8 | 0.84 |
N of metastatic sites, <2/≥2 | 61/9 | 31/12 | 0.04 * | 63/11 | 29/10 | 0.16 |
Liver metastases, absent/present | 38/32 | 17/26 | 0.12 | 36/38 | 19/20 | 0.99 |
Lung metastases, absent/present | 50/20 | 26/17 | 0.22 | 50/24 | 26/13 | 0.92 |
Bone metastases, absent/present | 61/9 | 32/11 | 0.08 | 60/14 | 33/6 | 0.64 |
LDH, <450/≥450 IU/L | 42/6 | 20/9 | 0.04 * | 42/10 | 20/5 | 0.93 |
Hb, ≥12/<12 g/L | 33/36 | 11/32 | 0.01 * | 34/39 | 10/29 | 0.03 * |
Albumin, ≥35/<35 g/L | 35/35 | 9/34 | 0.002 * | 31/43 | 13/26 | 0.37 |
Marks an association reaching statistical significance (p<0.05).