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. 2014 Jan 7;12(1):e1001759. doi: 10.1371/journal.pbio.1001759

Figure 3. Altered metabolic response in IFNAR−/− DCs.

Figure 3

(A) Bone marrow mixed-chimera mice were injected with 50 µg poly IC IP. 14 h later, DCs were FACS sorted based on CD45.2 expression and analyzed for gene expression with Illumina chips. Heat map represents expression values (2-fold change and FDR<0.05) of poly IC-treated WT (green), IFNAR−/− (orange) versus untreated DCs (blue). Each column represents an individual sample. (B) Pathway analysis was performed using GSEA (FDR<0.25). Table represents the top ten pathways upregulated in IFNAR−/− versus WT DCs.