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. 2014 Jan 7;9(1):e84785. doi: 10.1371/journal.pone.0084785

Table 2. Summary of variant calling following DNA sequencing.

WGA tumor TotalHetero TotalHomo RatioHetero/homo Transition/Transversion rate Coverage intarget regions Totalreads
118(T) 7359 4136 1.78 3.42 39.67 35.55 M
127(T) 8068 4627 1.74 3.32 72.28 37.43 M
140(T) 7904 4411 1.79 3.25 59.33 34.73 M
146(T) 8104 4247 1.91 3.23 61.05 34.47 M
210(T) 7806 4333 1.80 2.96 53.72 54.23 M
225(T) 8088 4258 1.90 2.91 83.70 43.54 M
247(T) 7091 3498 2.03 2.58 24.65 19.77 M
255(T) 7387 4215 1.75 3.29 62.69 33.76 M
278(T) 8328 4612 1.81 3.11 107.10 57.96 M
295(T) 7517 4451 1.69 3.24 48.06 28.13 M
322(T) 9019 4173 2.16 2.53 49.57 19.14 M
344(T) 8107 4300 1.89 3.08 59.31 29.42 M
396(T) 7408 4169 1.78 3.06 31.25 35.00 M
412(T) 8755 4752 1.84 2.84 98.08 45.19 M
421(T) 8552 4489 1.91 2.95 81.62 37.04 M
541(T) 9669 4511 2.14 3.11 35.20 37.75 M
Average 8073 4324 1.87 3.06 60.46 36.44 M
StDev 683 286 0.14 0.25 23.45 10.40
Unamplified tumor
118(T) 9006 4823 1.87 2.95 48.39 26.08 M
127(T) 14029 3152 4.45 3.27 87.78 32.40 M
140(T) 8725 4875 1.79 3.16 64.98 35.76 M
146(T) 15193 3123 4.86 3.18 85.07 29.08 M
210(T) 8860 5117 1.73 3.17 79.28 26.47 M
225(T) 14270 3081 4.63 3.30 73.46 24.50 M
247(T) 8879 5066 1.75 3.22 108.08 53.61 M
255(T) 8743 4891 1.79 3.26 81.93 42.86 M
295(T) 8717 5067 1.72 3.03 54.27 110.79 M
278(T) 8656 4998 1.73 3.21 88.89 47.00 M
322(T) 8650 4991 1.73 3.11 73.08 37.62 M
344(T) 14161 3006 4.71 3.15 77.05 26.14 M
396(T) 7627 4455 1.71 3.27 36.48 17.41 M
412(T) 8473 4940 1.72 3.21 73.48 38.37 M
421(T) 9085 4977 1.83 3.14 81.82 45.31 M
541(T) 10900 5329 2.05 3.17 73.85 37.67 M
Average 10248 4493 2.50 3.18 74.24 39.44 M
StDev 2574 855 1.29 0.09 17.11 21.30
WGA normal
118(N) 7476 4154 1.80 3.43 73.07 38.26 M
127(N) 9290 4619 2.01 2.64 101.20 23.63 M
140(N) 7288 3984 1.83 3.41 59.76 35.17 M
146(N) 8292 4613 1.80 3.32 67.14 37.40 M
210(N) 7894 4334 1.82 3.13 48.37 39.87 M
225(N) 11154 4935 2.26 2.07 127.39 75.50 M
247(N) 8925 4940 1.81 3.27 123.26 37.12 M
255(N) 8560 4771 1.79 3.25 83.78 26.35 M
295(N) 6506 3414 1.91 3.18 27.59 29.18 M
278(N) 6961 3966 1.76 3.10 30.67 28.21 M
322(N) 7747 4610 1.68 3.29 56.95 25.81 M
344(N) 8082 4298 1.88 3.09 60.13 17.95 M
396(N) 7276 4035 1.80 3.18 27.70 34.08 M
412(N) 8010 4156 1.93 2.84 38.52 26.65 M
421(N) 8561 4579 1.87 3.11 64.07 30.20 M
541(N) 10411 4840 2.15 3.03 78.53 46.44 M
Average 8277 4391 1.88 3.08 66.76 34.49 M
StDev 1224 423 0.15 0.34 30.79 13.08