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. 2014 Jan 7;9(1):e84478. doi: 10.1371/journal.pone.0084478

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© 2014 Ichimura et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Bright-field (left panel) and Raman images (right panel) of undifferentiated (A) and differentiated (B) ESCs. (C) Averaged Raman spectra of undifferentiated ESCs (blue), differentiated ESCs (red), and MSCs (green) in the fingerprint region (700–1800 cm⁻¹). For PCA analysis, raw spectra without averaging was used. Spectra shown are average of 18–44 cells.