Table 2. In vivo tumorigenicity of ovarian cancer spheroid cells.
| Cell type | Injection cell type | Injection site | Cell dose a | Tumor formation b | Latency c days |
| Primary | Spheroid | S.c. | 2000 | 4/4 | 31/38/42/90 |
| EOC | S.c. | 5000 | 3/3 | 40/52/54 | |
| RP-OV | S.c. | 10000 | 3/3 | 31/37/38 | |
| 17534 | Parental | S.c. | 5000 | 0/2 | – |
| S.c. | 10000 | 0/2 | – | ||
| S.c. | 40000 | 0/2 | – | ||
| Spheroid | I.p. | 10000 | 4/4 | 75/80/80/84 | |
| I.p. | 20000 | 3/3 | 59/63/63 | ||
| I.p. | 40000 | 3/3 | 54/54/63 | ||
| Parental | I.p. | 20000 | 0/2 | – | |
| I.p. | 40000 | 0/2 | – | ||
| I.p. | 60000 | 0/2 | – | ||
| I.p. | 80000 | 0/3 | – | ||
| I.p. | 1.7×107 | 1/1 | 92 | ||
| I.p. | 2×107 | 3/3 | 105 | ||
| EOC cell | Spheroid | S.c. | 2000 | 2/2 | 50/57 |
| line | Parental | S.c. | 2000 | 1/2 | 57 |
| OV2774 | Spheroid | I.p. | 5000 | 1/1 | 126 |
| I.p. | 15000 | 1/1 | 85 | ||
| I.p. | 20000 | 1/1 | 126 | ||
| I.p. | 300000 | 1/1 | 79 | ||
| Parental | I.p. | 20000 | 0/1 | – | |
| I.p. | 40000 | 0/1 | – | ||
| 1.2×107 | 1/1 | 50 | |||
| 2×107 | 1/1 | 38 |
a Number of cells per injection.
b Number of tumors formed per number of injection.
c The time from injection to the first appearance of a palpable tumor or ascites.
S.c.: subcutaneous; I.p.: intraperitoneal.