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. 2014 Jan 7;9(1):e84982. doi: 10.1371/journal.pone.0084982

Figure 6. Quantitation of orthotopic tumors.

Figure 6

COLO-357 cells were stably transduced with lentivirus expressing Tet-inducible control shRNA (shScramble) or DUSP1-targeting shRNA (shDUSP1). Cells were injected into the pancreata of immunodeficient mice, and 15 days later, tumors were imaged using a Vevo2100 high-resolution ultrasound. (A–B) Representative high-resolution ultrasound images (A) and quantitation of tumor volumes using 3D abdominal scans (B) show that prior to Dox or gemcitabine treatments, shScramble and shDUSP1 tumors (T, indicated by arrows) were similar in size. Data in (B) are the means ± SEM.