Table 2. Summary of TC-71 bioluminescent signal detection in live mice and post-mortem (after dissection).
Organ | In live mice | Post mortem |
femur | 12/13 | 4/4 |
lungs | 4/11 | 4/5 |
kidneys | 1/11 | 1/5 |
Liver/abdomen | 4/11 | 1/5 |
distant bone | 3/11 | 2/5 |
One mouse with an IVIS-positive femoral tumour was culled on day 4 and could not be assessed for metastatic spread. Post mortem bioluminescence imaging of dissected organs was performed on 5 animals. The involved leg of one of these had been removed before imaging.