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. 2014 Jan 7;9(1):e85248. doi: 10.1371/journal.pone.0085248

Table 1. Baseline characteristics of patients with early arthritis.

Rheumatoid artritis(n = 69) Undifferentiated arthritis(n = 22) Total(n = 91) P value
Age (years) 54 [45–66] 55 [44–69] 54 [45–66] n.s.
Female gender (%) 78 54 73 0.004
Disease duration (months) 5 [3][8] 7 [3][11] 5.4 [3.2–8.4] n.s.
GDAPa 46 [29–60] 46 [28–58] 46 [28–60] n.s.
GDAPh 50 [30 - 72] 30 [14–50] 42 [25–66] 0.002
VAS Pain 52 [25–70] 48 [13–60] 50 [20–70] n.s.
HAQ 1.125 [0.625–1.750] 0.875 [0.375–1.375] 1 [0.625–1.625] n.s.
TJC 6 [2][12] 3 [0–10] 6 [1][12] n.s.
SJC 7 [3][10] 3 [0–6] 5 [2][9] 0.004
ESR 32 [19–54] 17 [8–34] 30 [15–46] 0.006
CRP (mg/dl) 0.92 [0.2–1.96] 0.48 [0.1–0.82] 0.72 [0.16–1.7] 0.047
DAS28 (0–10) 5.0 [4.0–6.1] 3.6 [3.1–4.5] 4.8 [3.5–6.0] 0.002
RF (%) 54 18 45 0.004
ACPA+ (%) 60 14 49 <0.001
VIP (pg/ml) 342 [262–440] 375 [243–490] 352 [261–444] n.s.

Data are shown as the median or percentage. GDAPa: global disease assessment by patient; GDAPh: global disease assessment by physician; VAS: visual analog scale; HAQ: health assessment questionnaire; TJC: tender joint count; SJC: swollen joint count; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; DAS28∶28-joint count Disease Activity Score; RF: rheumatoid factor; ACPA: anti-citrullinated peptide antibodies; VIP: vasoactive intestinal peptide. n.s.: not significant.