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Anti-MHC class I-induced protein phosphorylation and Bcl-2 expression in the absence of complement. Lysates from of BALB/c cardiac allografts treated with anti-H-2Kd F(ab′)2 or intact anti-H-2Kd IgG were analyzed for phosphorylation of ERK Thr202/Tyr204 (A), S6K Thr421/Ser424 (B), Akt Ser473 (C), S6RP Ser235/236 (D), and mTOR Ser2448 (E) and Bcl-2 protein expression (F).
