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Demonstration of interrelationships between proteins involved in the MHC class I-signaling pathway in vivo. MDS analysis of protein phosphorylation data obtained by Western blot shows that S6K and Akt are closely linked and members of the mTOR pathway: mTOR, S6K, S6RP, are linked to Akt and related to each other. The great distance separating ERK from members of the mTOR pathway suggests multiple signaling inputs are required for ERK activation.
