Table 1. Mean levels of LINE-1 and Sat2 by subjects’ characteristics.
| % Methylation (Mean ± SD) | |||
|---|---|---|---|
| Variable |
N |
LINE1 |
Log(Sat2) |
| Age |
|
|
|
| Below Mean (≤ 51) |
508 |
75.5 ± 2.1 |
4.6 ± 0.6 |
| Above Mean (> 51) |
632 |
75.5 ± 2.1 |
4.6 ± 0.6 |
| p value |
|
0.86 |
0.15 |
| BMI (kg/m2) |
|
|
|
| Below Mean (≤ 24.1) |
591 |
75.4 ± 2.1 |
4.6 ± 0.6 |
| Above Mean (> 24.1) |
549 |
75.6 ± 2.1 |
4.6 ± 0.6 |
| p value |
|
0.20 |
0.31 |
| Gender |
|
|
|
| Female |
129 |
75.8 ± 1.8 |
4.8 ± 0.5 |
| Male |
1011 |
75.4 ± 2.2 |
4.6 ± 0.6 |
| p value |
|
0.06 |
0.0002 |
| Smoking |
|
|
|
| No |
603 |
75.6 ± 2.0 |
4.6 ± 0.6 |
| Yes |
535 |
75.5 ± 2.2 |
4.6 ± 0.6 |
| p value |
|
0.54 |
0.11 |
| Alcohol |
|
|
|
| No |
925 |
75.6 ± 2.0 |
4.6 ± 0.6 |
| Yes |
212 |
75.3 ± 2.4 |
4.6 ± 0.7 |
| p value |
|
0.28 |
0.19 |
| HBsAg |
|
|
|
| Negative |
686 |
75.4 ± 2.1 |
4.6 ± 0.6 |
| Positive |
454 |
75.7 ± 2.1 |
4.7 ± 0.6 |
| p value |
|
0.12 |
0.001 |
| Anti-HCV |
|
|
|
| Negative |
983 |
75.5 ± 2.1 |
4.6 ± 0.6 |
| Positive |
123 |
75.4 ± 2.0 |
4.6 ± 0.6 |
| p value | 0.57 | 0.45 | |
Smoking data missing on 2 subjects. Alcohol data missing on 3 subjects. Anti-HCV data missing on 34 subjects. One-way ANOVA test of the differences in the methylation markers among groups.