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. Author manuscript; available in PMC: 2014 Dec 26.
Published in final edited form as: Stat Methods Med Res. 2013 Jun 26;25(4):1596–1619. doi: 10.1177/0962280213492588

Table 5.

Trivariate model parameter estimates and standard errors

Se (SE) Sp (SE) Disease prevalence (SE) Test prevalence (SE) σμ (SE) σν (SE) σε (SE) ρμν (SE) ρεμ (SE) ρεμ (SE) AIC -2logL
model I 0.826 (0.041) 0.887 (0.021) 0.448 (0.075) 0.433 (0.058) 1.123 (0.236) 0.671 (0.203) 1.387 (0.260) 0 0 0 2653.8 2641.8
model II 0.827 (0.041) 0.888 (0.021) 0.448 (0.075) 0.433 (0.059) 1.130 (0.238) 0.673 (0.205) 1.387 (0.260) −0.311 (0.328) 0 0 2655.0 2641
model III 0.826 (0.042) 0.877 (0.026) 0.448 (0.076) 0.438 (0.062) 1.138 (0.241) 0.715 (0.235) 1.396 (0.263) 0 0 −0.401 (0.471) 2654.5 2640.5
model IV 0.822 (0.042) 0.887 (0.021) 0.447 (0.075) 0.430 (0.060) 1.109 (0.237) 0.678 (0.206) 1.383 (0.260) 0 0.176 (0.256) 0 2654.5 2640.5
model V 0.823 (0.042) 0.879 (0.026) 0.447 (0.075) 0.435 (0.062) 1.117 (0.240) 0.702 (0.229) 1.381 (0.260) 0 0.122 (0.270) −0.328 (0.547) 2656.2 2640.2
model VI 0.828 (0.042) 0.880 (0.025) 0.448 (0.076) 0.437 (0.062) 1.146 (0.244) 0.697 (0.223) 1.396 (0.263) −0.247 (0.340) 0 −0.325 (0.516) 2655.9 2639.9
model VII 0.823 (0.042) 0.888 (0.021) 0.447 (0.075) 0.429 (0.061) 1.114 (0.238) 0.681 (0.208) 1.384 (0.259) −0.284 (0.329) 0.165 (0.256) 0 2655.9 2639.9
model VIII 0.823 (0.042) 0.881 (0.025) 0.447 (0.075) 0.434 (0.064) 1.117 (0.239) 0.703 (0.226) 1.387 (0.261) −0.298 (0.323) 0.175 (0.256) −0.343 (0.502) 2657.5 2639.5

Model I–VIII is trivariate GLMM with all possible combinations of correlation parameters. Model I assumes all correlation coefficient ρμν,ρεμ and ρεν equal to 0. Model II, III, IV assume only one of the correlation coeffecients is not 0: ρμν ≠ 0, ρεν ≠ 0 and ρεμ ≠ 0, respectively. Model V–VII assumes two of the correlation coefficients are not 0: ρεμ ≠0 and ρεν ≠ 0, ρμν ≠0 and ρεν ≠ 0, ρμν ≠0 and ρεμ ≠ 0, respectively. Model VII assumes none of ρμν, ρεμ and ρεν are 0.