Table 3.

Adjusted Odds Ratios (95% Confidence Intervals) of Having Leptin and Resistin Levels in the Top Tertile, and Adiponectin Levels in the Bottom Tertile, Associated with Body Size Phenotypes

	Top Tertile of Leptin (21.0–138.6 ng/ml)			Top Tertile of Resistin (14.2–182.6 ng/ml)			Bottom Tertile of Adiponectin (0.0–21.8 μg/ml)
	OR	95% CI	p	OR	95% CI	p	OR	95% CI	p
Model 1
MBNW (n=372)	1.00	(reference)		1.00	(reference)		1.00	(reference)
ARNW (n=310)	2.51	1.25–5.07	0.014	1.46	1.03–2.07	0.036	2.87	1.95–4.24	< 0.001
Model 2
MBNW	1.00	(reference)		1.00	(reference)		1.00	(reference)
ARNW	1.96	0.95–4.04	0.067	1.50	1.05–2.15	0.027	2.53	1.70–3.76	< 0.001

Model 1 = adjusted for age, race, stroke case status, smoking, physical activity, and hormone therapy use

Model 2 = Model 1 + BMI

MBNW – Metabolically Benign Normal Weight Phenotype; ARNW – At-Risk Normal Weight Phenotype

The Metabolically Benign Phenotype was defined as ≤ 1 of: elevated blood pressure (≥130/85 mmHg or medication), elevated triglycerides (≥150mg/dL), elevated fasting glucose (≥100 mg/dL or medication), low HDL-C (<50mg/dL for women or medication).

The Metabolically At-Risk Phenotype was defined as ≥ 2 of: elevated blood pressure (≥130/85 mmHg or medication), elevated triglycerides (≥150mg/dL), elevated fasting glucose (≥100 mg/dL or medication), low HDL-C (<50mg/dL for women or medication). OR If diabetic (fasting blood glucose ≥ 126 mg/dl, or self-report of diabetes or on antidiabetic medication).