Table 4.
Agreement among the three companies in assigning individual consumers to the same risk category, according to the risk categories used by 23andMe
| Diseases | Assigned to the same risk category by all three companies
|
Assigned to the same risk category by two companies
|
Assigned to different risk categories
|
||||
|---|---|---|---|---|---|---|---|
| ↓↓↓ | --- | ↑↑↑ | ↑↑- ↓↓- |
--↑ --↓ |
↑↑↓ ↓↓↑ |
↑-↓ | |
| Age-related macular degeneration | 52.3 | 0.5 | 15.2 | 6.1 | 6.0 | 12.5 | 7.4 |
|
| |||||||
| Atrial fibrillation | 42.4 | 6.7 | 16.7 | 27.3 | 5.7 | 1.2 | 0.0 |
|
| |||||||
| Celiac disease | 75.3 | 0.0 | 13.8 | 9.0 | 0.4 | 1.3 | 0.3 |
|
| |||||||
| Crohn disease | 51.8 | 0.2 | 3.5 | 13.8 | 3.7 | 19.9 | 7.2 |
|
| |||||||
| Prostate cancer | 15.6 | 4.5 | 13.5 | 29.4 | 21.7 | 6.5 | 9.0 |
|
| |||||||
| Type 2 diabetes | 22.2 | 7.8 | 14.7 | 24.1 | 23.1 | 3.2 | 5.0 |
23andMe categorizes disease risks as decreased (↓), elevated (↑), and typical (-) risks if the risks of disease are lower than 20% below the average population risk, higher than 20% above the average population risk, and in between, respectively. Values are percentages. For example, ↓↓↓ indicates the percentage of individuals that were decreased risk according to all three companies, and ↑-↓ indicates the percentage risks in the three different risk categories.