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A) SEM digital image of aqueous silk MN (pyramid shape) fabricated by our previous method [43]. B) – F) SEM images of cone shaped MN prepared from an aqueous silk solution with different shapes and geometries. G) – I) SEM images of cone shaped MN made from solvent-based (hexafluoroisopropanol) silk solution with various shapes and sizes. J) and K) Microparticle-loaded aqueous silk MN from pyramid and cone shaped needles, respectively.
