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. Author manuscript; available in PMC: 2014 Jan 7.
Published in final edited form as: Stat Methods Med Res. 2012 Mar 15;25(1):101–117. doi: 10.1177/0962280212441965

Table 7.

Analysis results of Baylor AD dataset under various models.

Naive
M1
M2
PMSD 95% CI PMSD 95% CI PMSD 95% CI
Outcome model
 Int 0.683.353 −0.008, 1.374 −0.044.551 −1.200, 0.946 −0.7011.141 −3.831, 0.891
x 1.881.320 1.254, 2.507 2.674.520 1.762, 3.838 3.5391.180 1.887, 6.758
 Pre-prog −1.347.184 −1.707, −0.987 −1.681.241 −2.174, −1.222 −1.796.298 −2.431, −1.258
 Age −0.136.114 −0.360, 0.088 −0.175.148 −0.472, 0.104 −0.113.216 −0.491, 0.387
 IQ 0.606.116 0.379, 0.834 0.917.158 0.616, 1.241 0.868.212 0.445, 1.291
Exposure model
 Int 2.788.264 2.271, 3.304 2.864.278 2.347, 3.430 2.797.389 2.055, 3.598
 Pre-prog −0.603.200 −0.996, −0.211 −0.623.209 −1.034, −0.224 −0.719.259 −1.267, −0.245
 Age −0.404.141 −0.679, −0.128 −0.412.146 −0.711, −0.130 −0.508.202 −0.943, −0.155
 IQ 0.687.135 0.422, 0.953 0.680.140 0.406, 0.955 0.859.225 0.482, 1.370
MMSE
p 0.974.014 0.942, 0.997 0.973.017 0.934, 0.998
q 0.793.046 0.702, 0.881 0.771.052 0.666, 0.870
 ADAS
p 0.815.027 0.762, 0.869 0.809.029 0.752, 0.865
q 0.906.029 0.845, 0.960 0.883.038 0.803, 0.951
CDR-Total
p 0.993.005 0.980, 1.000 0.986.010 0.962, 0.999
q 0.982.017 0.936, 1.000 0.786.142 0.566, 0.996
CDR-SB
p 0.997.003 0.990, 1.000 0.989.008 0.969, 0.999
q 0.834.049 0.732, 0.923 0.664.118 0.504, 0.876

Naive: naive analysis which ignores misclassification and treats y1 and x1 as y and x, respectively; M1: the model assuming conditional independence in both measurements of y and x; M2: the model assuming conditional dependence in both measurements of y and x; pre-prog: log pre-progression rate; age: standardized age; IQ: standardized premorbid IQ; CI: Credible interval; MMSE: Mini-Mental Status Exam; ADAS: Alzheimers Disease Assessment Scale-Cognitive Subscale; CDR-Total: Clinical Dementia Rating Scale-Total; and CDR-SB: Clinical Dementia Rating Scale-Sum of Boxes.