. Author manuscript; available in PMC: 2015 Mar 20.

Published in final edited form as: Oncogene. 2013 Apr 22;33(12):1538–1547. doi: 10.1038/onc.2013.102

Table 1.

Tumor incidence in Control, Tgfbr2^IEKO, Pten^IEKO and Pten^IEKO;Tgfbr2^IE^KO mice

Genotype	Number of mice	Number of mice with hyperplastic lesions	Number of mice with adenocarcinomas	Number of hyperplastic lesions	Number of adenocarcinomas
Control^#	20	0	0	0	0
Tgfbr2^IEKO	20	0	0	0	0
Pten^IEKO	39	2^€	1^λ	3	1
Pten^IEKO; Tgfbr2^IEKO	43	4^μ,^£.^¥	35^δ,^&.^¥	4	49

Control = wild-type mice, matched strain background

^€

P = 0.54, Pten^IEKO (2/39) vs. Control (0/20), Fisher’s exact test

^λ

P = 1.0, Pten^IEKO (1/39) vs. Control (0/20), Fisher’s exact test

^μ

P = 0.30, Pten^IEKO; Tgfbr2^IEKO (4/43) vs. Control (0/20), Fisher’s exact test

^£

P = 0.68, Pten^IEKO; Tgfbr2^IEKO (4/43) vs. Pten^IEKO (2/39), Fisher’s exact test

^δ

P < 0.0001, Pten^IEKO; Tgfbr2^IEKO (35/43) vs. Control (0/20), Fisher’s exact test

P < 0.0001, Pten^IEKO; Tgfbr2^IEKO (35/43) vs. Pten^IEKO (1/39), Fisher’s exact test

^¥

N=2 mice developed one adenocarcinoma and one hyperplastic lesion with dysplasia