Table 1.
Baseline characteristics of study participants. Values are shown as mean ± SE. P-value shown in the right column refers to differences between the Diabetes Support and Education (DSE) and RYGB group at baseline.
| Variable | DSE | Roux-en-Y Bypass | P-value |
|---|---|---|---|
| n | 31 | 30 | |
| Female, % | 67.7 | 66.7 | 0.929 |
| Age, years | 47.4 ± 1.5 | 49.6 ± 1.4 | 0.292 |
| Weight, kg | 114.3 ± 3.1 | 120.1 ± 3.1 | 0.186 |
| BMI, kg/m2 | 40.1 ± 0.9 | 43.4 ± 0.8 | 0.006 |
| Waist circumference, cm | 122.7 ± 2.3 | 130.3 ± 2.2 | 0.018 |
| Percent body fat,% | 42.0 ± 1.1 | 44.4 ± 1.1 | 0.159 |
| Fat free mass, kg | 63.6 ± 15.7 | 63.0 ± 20.5 | 0.798 |
| Trunk fat, % | 43.7 ± 1.2 | 47.4 ± 1.1 | 0.030 |
| Fat-to-FFM ratio | 0.73 ± 0.03 | 1.07 ± 0.25 | 0.159 |
| HbA1c, % | 7.51 ± 0.23 | 7.53 ± 0.23 | 0.943 |
| Fasting glucose, mg/dL | 149.1 ± 9.2 | 155.6 ± 8.6 | 0.607 |
| Fasting insulin, uU/mL | 16.9 ± 2.6 | 21.9 ± 5.4 | 0.401 |
| Insulin sensitivity, mU/L-1.min−1 | 1.39 ± 0.21 | 1.48 ± 0.22 | 0.753 |
| Acute insulin response, mU−1.min | 93.3 ± 28.6 | 71.7 ± 26.8 | 0.684 |
| Disposition index | 95.2 ± 27.7 | 77.6 ± 61.0 | 0.796 |
| Glucose effectiveness, | 11.6 ± 1.0 | 12.3 ± 1.0 | 0.626 |
| Free fatty acid, umol/L | 700.4 ± 31.4 | 757.6 ± 48.4 | 0.486 |
| hsCRP, mg/dL | 1.20 ± 0.40 | 0.86 ± 0.19 | 0.448 |
| Anti-diabetes medication, % | 0.875 | ||
| Oral agents | 71 | 73 | |
| Insulin therapy | 29 | 27 |