Table 3.

Changes from baseline to 12-month of follow-up in glucose homeostasis, lipoprotein profiles, body composition following RYGB surgery between insulin and non-insulin users at baseline. Values are shown as mean ± SE. P-values refer to the comparison between insulin and non-insulin users.

	Non-insulin users	Insulin users	P value
N	22	8
Age, years	50.2 ± 1.8	48.0 ± 1.6	0.342
Body weight, kg	−33.5 ± 2.2	−33.7 ± 5.1	0.969
Body mass index, kg/m2	−12.5 ± 0.2	−11.5 ± 1.5	0.525
Waist circumference, cm	−26.4 ± 2.3	−27.4 ± 4.5	0.837
Percent body fat,%	−11.5 ± 1.2	−10.3 ± 2.5	0.619
Fat free mass, kg	−8.32 ± 0.87	−7.76 ± 1.13	0.738
Trunk fat, %	−13.5 ± 1.7	−12.9 ± 3.4	0.858
Total fat-to-FFM ratio	−0.66 ± 0.33	−0.27 ± 0.08	0.521
HbA1c, %	−1.01 ± 0.29	−1.79 ± 0.39	0.181
Fasting glucose, mg/dL	−39.5 ± 10.3	−52. 0 ± 15.8	0.572
Fasting insulin, uU/L	−16.1 ± 3.6	−26.7 ± 21.6	0.408
Free fatty acids, umol/L	−167.3 ± 81.1	−115.3 ± 123.6	0.745
hsCRP, mg/L	−0.56 ± 0.23	−0.46 ± 0.21	0.821
Insulin sensitivity, mU/L−1.min−1	2.54 ± 0.62	2.45 ± 0.45	0.939
Acute insulin response, mU−1.min	29.0 ± 19.5	49.9 ± 43.0	0.640
Disposition index	246.6 ± 73.1	112.7 ± 80.1	0.381