Table 1.
Demographic and clinical characteristics of 76 NSCLC patients and the association with miR-486-5p expression in tumor tissue specimens
| Characteristics | Number of cases (%) | Median expression of miR-486-5p (mean±s.d.) | P |
|---|---|---|---|
| Age, year | |||
| ≥69 | 46 (60.5) | 0.03182±0.03206 | 0.18608 |
| <69 | 30 (39.5) | 0.02165±0.00276 | |
| Gender | |||
| Male | 56 (73.7) | 0.03083±0.04577 | 0.26550 |
| Female | 20 (26.3) | 0.02017±0.03556 | |
| Histology | |||
| Adenocarcinomas | 39 (51.3) | 0.02816±0.04354 | 0.19643 |
| Squamous cell carcinomas | 37 (48.7) | 0.02253±0.02902 | |
| Smokersa | |||
| Yes | 69 (90.8) | 0.02126±0.03763 | 0.16601 |
| No | 7 (9.2) | 0.03015±0.02010 | |
| T-status | |||
| 1a | 13 (17.1) | 0.03557±0.04555 | 0.34540 |
| 1b | 9 (11.8) | 0.03106±0.02678 | |
| 2 | 34 (44.8) | 0.03264±0.04135 | |
| 3 | 15 (19.7) | 0.03936±0.03584 | |
| 4 | 5 (6.6) | 0.03309±0.03276 | |
| N-statusb | |||
| No | 30 (39.5) | 0.02829±0.05080 | 0.00190 |
| Yes | 46 (60.5) | 0.01503±0.01916 | |
| Stage | |||
| I | 19 (25.0) | 0.07665±0.04979 | 0.00010 |
| II | 33 (43.4) | 0.02830±0.01585 | |
| III | 24 (31.6) | 0.01008±0.00746 | |
Abbreviation: NSCLC, non-small-cell lung cancer.
a
Smokers were defined as persons who had smoked a 20 pack year, or greater.
b
Lymph node status was classified as N0, N1, N2 and N3. In the present study, N1, N2 and N3 are considered to be ‘Yes’, whereas N0 is considered as ‘No’.