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. Author manuscript; available in PMC: 2014 Jun 19.
Published in final edited form as: J Cyst Fibros. 2012 Dec 20;12(2):116–124. doi: 10.1016/j.jcf.2012.11.010

Table 1.

Proposed classification of CFLD.

  1. CF related liver disease with cirrhosis/portal hypertension (based on clinical exam/imaging, histology, laparoscopy)

  2. Liver involvement without cirrhosis/portal hypertension consisting of at least one of the following:
    1. Persistent AST, ALT, GGT >2 times upper limit of normal
    2. Intermittent elevations of the above laboratory values
    3. Steatosis (histologic determination)
    4. Fibrosis (histologic determination)
    5. Cholangiopathy (based on ultrasound, MRI, CT, ERCP)
    6. Ultrasound abnormalities not consistent with cirrhosis

  3. Preclinical: No evidence of liver disease on exam, imaging or laboratory values