Table 5.
List of significantly up-regulated and down-regulated genes >1.5 fold in Temozolomide-treated U87cells (p<0.05).
| Up-regulated Genes | ||||
|---|---|---|---|---|
| Entrez | Symbol | Title | Fold Change | Function |
| 1026 | CDKN1A | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 1.82 | Cell cycle inhibitor |
| 10628 | TXNIP | Thioredoxin interacting protein TXNIP | 1.62 | Thioredoxin inhibitor; tumor suppressor |
| 3486 | IGFBP3 | Insulin-like growth factor binding protein 3 (IGFBP3) | 1.61 | Cell growth |
| Down-regulated genes | ||||
| 5055 | SerpinB2 | Serpin peptidase inhibitor, clade B, | 0.57 | Inhibition of member 2 apoptosis |