. Author manuscript; available in PMC: 2015 May 1.

Published in final edited form as: Magn Reson Med. 2013 Jun 27;71(5):1863–1873. doi: 10.1002/mrm.24846

Table 2.

Effect of oxygen and carbogen breathing on BOLD and TOLD MRI

		BOLD (%ΔSI)		ΔT₂^*(ms)		TOLD (%ΔSI)		ΔpO₂ (torr)		HF₅ (%)
Rat #	Size (cm³)	Oxygen	CB	Oxygen	CB	Oxygen	CB	Oxygen	CB	Oxygen	CB
1	0.7	2.7±1.2^*	0.5±1.2	2.0±1.9^*	3.4±2.65^*	−1.0±2.4	−3.9±2.3^*	14.1±7.4^*	15.5±3.5^*	79 to 62	67 to 56
2	0.6	8.2±2.9^*	3.0±0.9^*	2.9±1.3^*	0.9±0.7^*	−0.4±1.4	−2.8±2.0^*	29.0±7.1^*	13.8±3.8^*	43 to 38	28 to 28
3	0.6	5.3±1.8^*	4.3±1.19^*	0.5±0.4^*	0.1±0.4	0.5±1.1	−1.5±2.2^*	10.0±3.6^*	7.3±1.3^*	53 to 41	50 to 48
4	0.5	18.7±5.3^*	20.0±0.8^*	2.4±0.6^*	2.5±0.2^*	7.3±2.2^*	8.7±1.9^*	35.2±2.7^*	36.4±1.6^*	66 to 29	45 to 31
5	0.5	4.3±1.4^*	4.7±1.5^*	1.2±0.7^*	0.6±0.7^*	1.2±1.0^*	1.6±0.7^*	7.1±1.3^*	15.2±1.2^*	43 to 17	27 to 14
6	0.7	1.2±2.1	3.8±1.4^*	0.3±0.5	1.1±0.6^*	0.2±0.8	2.1±1.3^*	3.6±1.0^*	6.8±3.6^*	63 to 41	49 to 32
7	3.0	−1.7±0.7^*	−1.4±0.8^*	−1.6±0.9^*	−2.1±1.3^*	−1.1±0.8^*	−3.1±1.2^*	−0.3±1.5	−3.0±0.3	97 to 95	97 to 97
8	2.9	−1.4±1.1^*	−1.5±1.3^*	−0.9±2.4	−2.8±4.0^*	−0.3±0.9	−1.9±1.3^*	2.6±1.0^*	4.8±0.5^*	95 to 92	94 to 92
9	8.8	2.8±0.8^*	1.7±0.7^*	4.8±2.3^*	6.9±2.8^*	0.7±0.5^*	−0.3±0.7	−1.2±0.4^*	−0.6±0.5	96 to 96	96 to 87
Average		4.4±6.2	3.8±6.6	1.3±2.0	1.2±2.9	0.8±2.5	−0.1±3.9	11±13	11±12	71 to 57	61 to 54

Quantitative pO₂ measurements were obtained using FREDOM and HF₅ was calculated.

p<0.01