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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: Free Radic Biol Med. 2013 Mar 5;0:179–196. doi: 10.1016/j.freeradbiomed.2013.02.006

Fig. 5.

Fig. 5

Effects of lactational exposure to CrIII on vitamin C, GST, GPx, and GR in plasma and ovary of F1 offspring. Experimental details are described under Materials and methods. Vitamin C, GPx, GST, and GR were measured in plasma and the whole ovary extracts from rats that were exposed to CrIII through mother’s milk between PND 1 and 21. Vitamin C in (A) plasma and (B) ovary; GST in (C) plasma and (D) ovary; GPx in (E) plasma and (F) ovary; and GR in (G) plasma and (H) ovary of PND 25, PND 45, and PND 65 rats exposed to CrIII lactationally through mother’s milk. Cr treatment decreased vitamin C, GPx, and GR and increased GST in plasma and ovary of F1 offspring in a dose-dependent manner, and vitamin C mitigated or inhibited the effects of CrIII, except on GST. aControl vs CrVI; bCrVI vs CrVI+vitamin C. Each value represents the mean±SEM of 20 rats, P<0.05.