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. Author manuscript; available in PMC: 2014 Sep 5.
Published in final edited form as: Free Radic Biol Med. 2013 Mar 5;0:179–196. doi: 10.1016/j.freeradbiomed.2013.02.006

Fig. 8.

Fig. 8

Effects of exposure to CrVI on vitamin C, GPx, GST, and GR in GCs, SIGCs, and TCs. GCs, TCs, and SIGCs were cultured and treated with CrVI with or without vitamin C pretreatment, as described in the legend to Fig. 7. Histograms depict vitamin C in (A) GCs, (B) SIGCs, and (C) TCs; GPx in (D) GCs, (E) SIGCs, and (F) TCs; GST in (G) GCs, (H) SIGCs, and (I) TCs; and GR in (J) GCs, (K) SIGCs, and (L) TCs. CrVI treatment decreased vitamin C, GPx, GST, and GR in GCs, SIGCs, and TCs in a time-dependent manner, and vitamin C pretreatment mitigated or inhibited the effects of CrVI treatment. Each value is the mean±SEM of three different plates per treatment, P<0.05. aCrVI treatment, 0 h vs 12 or 24 h; bCrVI+vitamin C, 0 h vs 12 or 24 h; cCrVI (12 or 24 h) vs CrVI+vitamin C (12 or 24 h).