Table 1.
Cardiovascular cell-specific expression of Nox isoforms.
| Cell type | Nox isoform | Tissue | Ref. |
|---|---|---|---|
| VSMCs | Nox1 | Mouse, rat aorta | [261,254,260] |
| VSMCs | Nox1 | Human coronary artery | [10] |
| VSMCs | Nox2 | Human resistance artery | [270] |
| VSMCs | Nox4 | Mouse, rat aorta | [271,272] |
| VSMCs | Nox4 | Human aorta | [273] |
| VSMCs | Nox4 | Human coronary artery | [10] |
| VSMCs | Nox5 | Human aorta | [277] |
| VSMCs | Duox1 | Human aorta | [280] |
| Endothelial cells | Nox1 | Human coronary artery | [10] |
| Endothelial cells | Nox1 | Human umbilical vein | [262] |
| Endothelial cells | Nox2 | Mouse, rat aorta | [263,264] |
| Endothelial cells | Nox2 | Human coronary artery | [10] |
| Endothelial cells | Nox2 | Human umbilical vein | [265,266] |
| Endothelial cells | Nox4 | Rat aorta | [264] |
| Endothelial cells | Nox4 | Human coronary artery | [10] |
| Endothelial cells | Nox4 | Human heart | [10] |
| Fibroblasts | Nox1 | Human heart | [10] |
| Fibroblasts | Nox2 | Human coronary artery | [10] |
| Fibroblasts | Nox2 | Human heart | [10] |
| Cardiomyocytes | Nox2 | Mouse, rat heart | [265,269] |
| Cardiomyocytes | Nox4 | Mouse heart | [275] |