Table 2.
Baseline Characteristics of Michigan Study of Women’s Health Across the Nation (SWAN) Women Overall and by Knee Cartilage Defect Severity From Magnetic Resonance Imaging at Follow-Up Visit 11.
| Cartilage Defect Score | ||||||
|---|---|---|---|---|---|---|
| Overall | None, internal signal alteration only |
Defect < 50% thickness |
Defect 50–99% thickness |
Defect 100% thickness |
P-value | |
| Mean (SD) |
Mean (SD) |
Mean (SD) |
Mean (SD) |
Mean (SD) |
||
| Age (years) | 46.1 (2.8) |
46.0 (3.5) |
45.8 (2.6) |
46.3 (3.0) |
46.2 (2.7) |
0.42 |
| Weight (kg) | 86.2 (22.0) |
69.6 (12.7) |
80.0 (20.2) |
85.0 (21.1) |
99.8 (20.8) |
<0.0001 |
| Height (cm) | 163.5 (6.2) |
163.9 (4.8) |
163.7 (5.6) |
163.0 (6.1) |
163.9 (7.1) |
0.67 |
| BMI (kg/m2) | 32.2 (8.1) |
25.9 (4.8) |
29.8 (7.4) |
32.0 (7.5) |
37.3 (7.9) |
<0.0001 |
| Waist circumference (cm) | 94.3 (17.0) |
81.5 (7.3) |
89.3 (15.9) |
94.0 (15.6) |
104.2 (16.9) |
<0.0001 |
| Hip circumference (cm) |
114.0 (16.3) |
102.3 (11.5) |
109.6 (14.7) |
112.8 (15.4) |
124.3 (16.0) |
<0.0001 |
| Waist:hip ratio | 0.82 (0.07) |
0.80 (0.07) |
0.81 (0.07) |
0.83 (0.07) |
0.84 (0.07) |
0.03 |
| Fat mass (kg) | 37.0 (16.7) |
23.6 (9.2) |
33.0 (14.8) |
36.2 (15.8) |
46.1 (17.8) |
<0.0001 |
| Skeletal muscle mass (kg) |
21.7 (3.4) |
20.5 (1.7) |
20.9 (3.3) |
21.5 (3.3) |
23.5 (3.1) |
<0.0001 |
|
n (%) |
n (%) |
n (%) |
n (%) |
|||
| Obese (BMI≥30 kg/m2) | 203 (56.1%) |
1 (12.5%) |
63 (44.4%) |
69 (54.3%) |
70 (82.4%) |
<0.0001 |
| Current Smoker | 87 (24.2%) |
2 (25.0%) |
35 (25.0%) |
36 (28.4%) |
14 (16.7%) |
0.28 |
| Ethnicity | ||||||
| African-American | 227 (62.4%) |
7 (87.5%) |
88 (61.5%) |
79 (62.2%) |
53 (61.6%) |
0.53 |
| Caucasian | 137 (37.6%) |
1 (12.5%) |
55 (38.5%) |
48 (37.8%) |
33 (38.4%) |
|
| Menopause Status | ||||||
| Premenopausal | 182 (50.3%) |
3 (37.5%) |
77 (53.9%) |
64 (50.8%) |
38 (44.7%) |
0.51 |
| Early Perimenopausal |
180 (49.7%) |
5 (62.5%) |
66 (46.2%) |
62 (49.2%) |
47 (55.3%) |
|