TABLE 1.
Characteristics of study participants in the Nurses’ Health Study in 1990 according to postmenopausal hormone use1
| Characteristic | Never used hormones (n = 27,034) | Current use, estrogen with progestin (n = 6224) | Difference2 |
| % | |||
| Parental myocardial infarction before the age of 60 y, % | 29.6 | 20.6 | −30 |
| Hypertension, % | 32.9 | 27.3 | −17 |
| Diabetes mellitus, % | 5.8 | 2.7 | −53 |
| High serum cholesterol3, % | 35.6 | 41.6 | 17 |
| Moderate smoker4, % | 9.4 | 4.6 | −51 |
| Bilateral oophorectomy, % | 4.2 | 8.9 | 112 |
| Past use of oral contraceptives, % | 30.6 | 46.4 | 52 |
| Multivitamin use, % | 24.6 | 42.2 | 72 |
| Vitamin E use, % | 9.5 | 18.1 | 91 |
| Aspirin use, % | 33.6 | 48.3 | 44 |
| Mean age, y | 60.1 | 56.7 | −6 |
| Mean age at menopause, y | 50.9 | 49.2 | −3 |
| Mean BMI, kg/m2 | 26.3 | 24.3 | −8 |
| Mean alcohol consumption, g/d | 4.7 | 6.0 | 28 |
| Mean consumption of saturated fat, g/d | 31.2 | 41.4 | 33 |
1
Adapted with permission from Grodstein et al. (27).
2
Calculated as 100 × (value in current-user group – value in never-used group)/value in never-used group.
3
Defined as ≥200 mg/dL.
4
Defined as 15–24 cigarettes/d.