Table 2.
Enavatuzumab treatment induced more gene expression changes in sensitive cell lines than in resistant lines.
| Number of genes up or down >2-fold |
||||
|---|---|---|---|---|
| Sensitive lines |
Resistant lines |
|||
| MDA-MB-468 | BT549 | T47D | BT20 | |
| 6 h | 51 | 126 | 1 | nt |
| 24 h | 50 | 408 | 9 | nt |
| 48 h | 329 | 648 | 15 | 3 |
| 72 h | 445 | 766 | 13 | nt |
The total number of genes whose expression is altered more than twofold up or down following enavatuzumab treatment at each time point is displayed.
nt, not tested. Analysis of BT20 cells was performed only at 48 h.