Table 1.
History of patients who underwent reirradiation of recurrent meningiomaa
| Patient No. | Age (Y) | Tumor location | Treatment prior to irradiation | Reirradiation | Treatment/s following reirradiation |
|---|---|---|---|---|---|
| 1 | 73 | Rt parafalcine | R (4 Y), SRS (16 Gy, 2 Y) | SRS to 15 Gy | None |
| 2 | 59 | L CPA angle | R (2 Y, grade 1), fSRT (1.5 Y, 54 Gy) | fSRT to 50.4 Gy | None |
| 3 | 47 | Rt mid cranial fossae | R (8 Y), SRS (15 Gy, 8 Y), R (3 M, grade 1) | SRS to 15 Gy | Reirradiation (5 Y) |
| 4 | 68 | L frontoparietal | fSRT (54 Gy, 7 Y) | SRS to 14 Gy | None |
| 5 | 33 | L optic nerve | R (3.5 Y, grade 1), fSRT (54 Gy, 2.5 Y) | fSRT to 50.4 Gy | None |
| 6 | 42 | L frontal/sphenoid | SRS (16 Gy, 4 Y) | fSRT to 54 Gy | R (3 Y) |
| 7 | 62 | Rt ant cranial fossa | R (5 Y, grade 1), SRS (14 Gy, 3 Y), R (2 Y), R (2 M) | fSRT to 46.8 Gy | None |
| 8 | 59 | L cavernous sinus | fSRT (54 Gy, 5 Y), R (4 M, grade 1) | fSRT to 50.4 Gy | None |
| 9 | 52 | Rt sphenoid wing | R (7.5 Y, grade 1), fSRT (54 Gy, 4 Y) | SRS to 14 Gy | None |
| 10 | 44 | L ONS | fSRT (50.4 Gy, 6 Y) | fSRT to 41.4 Gy | None |
| 11 | 57 | Rt sphenoid wing | Biopsy (4 Y, grade 1), fSRT (52.2 Gy, 4 Y) | fSRT to 45 Gy | None |
| 12 | 75 | L parasagittal | R (1 Y, grade 1), SRS to 18 Gy (4 M), R (3 M) | SRS to 18 Gy | Reirradiation (10 M), R (6 Y) |
| 13 | 67 | Rt occipital | R (3 Y, grade 3), fSRT (56 Gy, 3 Y) | SRS to 18 Gy | SRS (3.5 Y), RT (6.5 Y, grade II) |
| 14 | 61 | L temporal–parietal | R (5 Y, 1.5 Y, grade 3), fSRT (54 Gy, 15 M), R (2 M, grade 3) | fSRT to 35 Gy | R (10 M, grade 1), SRS (13 M, 16 Gy) |
| 15 | 53 | Bifrontal | SRS (14 Gy, 4 Y), R (1 Y, grade II) | fSRT to 54 Gy | R (1 Y, grade 3), reirradiation (1 Y), R (2 Y) |
| 16 | 78 | L frontal | R (1.5 Y, grade II), SRS (10 M, 15 Gy) | SRS to 18 Gy | SRS (2.5 Y, 15 Gy) |
| 17 | 69 | Rt infratemporal fossae | R (9 Y), fSRT (64.8 Gy, 3.5 Y), R (2.5 Y, 5 M, grade 3) | SRS to 18 Gy | SRS (7 M, 14 Gy) |
| 18 | 34 | Rt sphenoid wing | R (2.5 Y, 6 M), fSRT (41 Gy, 2 Y) | SRS to 14 Gy | R (9 M, 14 M, grade 3) |
| 19 | 73 | Bilateral parasagittal | R (3 Y, grade 3), SRS (15 Gy, 2 Y) | SRS to 14 Gy | None |
a
The disease course of each patient is shown in Figure 1.
Ant = anterior, CPA = cerebellopontine angle, fSRT = fractionated stereotactic radiotherapy, L = left, M = months, ONS = optic nerve sheath, R = resection, Rt = right, SRS = stereotactic radiosurgery, Y = years