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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Gene Ther. 2013 Jul 11;20(12):10.1038/gt.2013.40. doi: 10.1038/gt.2013.40

Figure 6.

Figure 6

IL-12 and IFN-γ expression in serum and tumors. C57BL/6 male mice bearing subcutaneous TRAMP-C2 tumors were injected intratumorally with saline (phosphate-buffered saline), Ad5-yCD/mutTKSR39rep (− IL-12; 1 × 109 PFU) or Ad5-yCD/mutTKSR39rep-mIL12 (+ IL-12; 3.5 × 107 PFU, 5 × 108 PFU, 1 × 109 PFU) on day 0. Serum and tumor were harvested on days 4 and 7. IL-12 and IFN-γ levels in serum (panels a and b) and clarified tumor lysates (panels c and d) were quantified by ELISA. The results represent the mean of five mice per group ± s.d. except for Ad5-yCD/mutTKSR39rep-mIL12 at 1 × 109 PFU in which there were only four animals per group.